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Gemfibrozil;Lopid;5-(2,5-Dimethylphenoxy)-2,2-Dimethylpentamoic Acid;2,2-Dimethyl-5-(2,5-Dimethylphenoxy) Valeric
Molecular formula : C15H22O3
MW : 250.35
CAS No. :25812-30-0

nature : colorless crystal. 61-63 ° C melting point, boiling point, 158-159 ° C (2.66 × 10-calf).

Preparation : 1. From 2,5 - dimethyl phenol and bromochloropropane produced by the reaction of 1-(2,5-dimethoxy-phenyl) -1,4-3-chloro-propane. Reaction in toluene, and the new Kit eliminate refluxed 5h. 2. By iso sodium and lithium differences converge amine formed by reaction of butyl lithium generation. 3. From 1-(2,5-dimethoxy-phenyl) -1,4-3-chloropropane and lithium substituting different acid synthesis phenoxy acid. These two intermediates in the mixed 10-15 ° Cslowly, stirring for 15 minutes. Then warming to 30 ° C, the reaction was kept 5h.

purposes : the goods to phenoxy acid-fang Antihyperlipidemics. Phenoxyacetic acid-fang Antihyperlipidemics in clofibrate on the basis of development. Including fenofibrate. Lipid benefits, will drop esters, such as phenoxyacetic acid. Such drugs in the chemical structure is similar. Clofarabine more serious adverse reactions (with increased incidence of gallstone phenomenon), improved varieties role than clofarabine strong, but fewer adverse reactions lighter.


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Structure:
More Detailed Data:
1) 2,2-dimethyl-5-(2,5-xylyloxy)-valeric acid;5-(2,5-Dimethylphenoxy)-2,2-Dimethylpentamoic Acid;2,2-dimethyl-5-(2,5-dimethyl phenoxy)valeric
2) Gemfibrozil
3) Gemfibrozil
4) Gemfibrozil
5) Gemfibrozil
6) gemfibrozil
7) Gemfibrozil Tablets
8) Gemfibrozil Capsules
9) valeric acid;pent(an)oic acid
10) valeric acid;pent(an)oic acid
Notice Some description was translated by software and the data is only as a reference.
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