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CAS : 54-42-2
formula : C9H11IN2O5
MW : 354.12
Melting Point : 155-180 ° C
Chinese name : iodine Gan; Net herpes; Iodine deoxy acridine; 5-iodo-2 '- delinking oxygen uridine
English name : 1-(2-deoxy-beta-d-ribofuranosyl) - 5-iodouracil; 1-beta-d-2'-deoxyribofuranosyl-5-iodouracil; 2'-deoxy-5 - iodouridine; 5-iodo-2'-deoxyuridine; 5-iododeoxyuridine; 5-iodouracil deoxyriboside; 5iudr; dendrid; emanil; herpesil; herpidu; herplex; herplex liquifilm
nature Description : white or category of white crystalline powder. Melting point 190-195 ° C (decomposition). Very little insoluble in water, soluble in chloroform little; Ether slightly soluble in ethanol; Acetone. In acidic aqueous solution stability, and solution-case autoclave was decomposition.
production methods : There are several methods of production. From Propargyl Alcohol, through oxidation; Esterification, with 2-amino-oxazoline nucleoside available cyclization of 2,2 - oxo pyrimidine nucleosides and then acylation; Bromide; Catalytic hydrogenation; Hydrolysis from iodine glycosides. From intensive fish can be produced from the 5'-deoxy-nucleotide cytosine, after further processing can be obtained iodine glycosides.
purposes : antiviral drugs for herpes simplex and herpes keratitis such as encephalitis.
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