CAS : 3703-76-2
formula : C20H24ClNO
molecular weight : 329.88
Chinese name : cough-ping; droperidol small chlorine; cough stability; 1-[2-α (-benzyloxy-4-chlorophenyl) - 2-yl] small Piperidine
English title : 1- (2 - ((p-chloro-alpha-phenylbenzyl) oxy) ethyl) - piperidin; 1-(2 - ((4-chlorophenyl) phenylmethoxy) ethyl) piperidine; cloperastine ; 1-(2 - ((4-chlorophenyl) phenylmethoxy) ethyl) - piperidin; 1-[2-[p-email-phenylbenzyl) - oxy] ethy] piperidine; p-Chlorobenzhydryl2 - (1-piperidyl) - ethyl ether
traits Description : boiling point 178-180 ° C (2:45, 3:59, 5:41) ,172-174 ° C (dimple), hydrochloride, C20H24CINO HCI, Hustazol. White or category of white crystalline powder. 147.9 ° C melting point. Water-soluble; Ethanol; Chloroform, acetone - soluble. No foul, Pungent base after a numb feeling.
production methods : from 4-chloro-benzene methanol by the ether; Condensation derived. 4-chloro-benzene methanol; Chloroethanol; By adding sulfuric acid and benzene 11:50, stirring, heating return 4h. Still, the minutes from organic layer. Using alkaline washing after washing solution to neutral, recovery of benzene 4-chloro-dibenzo-methyl-β - chloroethyl ether. With its Hexahydropyridine anhydrous sodium carbonate and heated to return seven hours, or cough-generated, refined salt that at hydrochloride.
purposes : non-narcotic, Pfizer applied to cold, flu, bronchitis, tuberculosis, lung cancer and other diseases caused by coughing.
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