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CAS : 110-85-0
formula : C4H10N2
molecular weight : 86.14
boiling point : 145-146 ° C
melting point : 108-112 ° C
Chinese name : piperazine
- dimethylamine
tetracarboxylic diamine
right has two nitrogen Central
two diamine
piperazine pyrazine
anhydrous piperazine
of two others in Central
English title : Piperazine
1,4-diazacyclohexane
b _ traits Description : clams thoroughly colorless needle or blade crystallization. The temperature of 106 ° C (Anhydrous), 44 ° C (hydrate). The boiling point of 146 ° C (Anhydrous) ball-130 ° C (hydrate), the refractive index 1.446 (113 ° C). The flash point of 109 ° C, soluble in water, soluble in alcohol, ether insoluble. 10% aqueous solution of pH 10.8-11.8.
production methods : by chloroethanol by ammonification, Central synthetic piperazine hydrochloride, which use sodium hydroxide and water system in six piperazine.
purposes : pharmaceutical intermediates, mainly for the production of anthelmintics piperazine-phosphate, citrate piperazine, and fluoride Fen and quiet, it hurts set, rifampicin.六水哌嗪溶于乙醇，加入冰醋酸搅拌冷却即析出乙酸哌嗪，被用于合成激素类药物氢化泼尼松磷酸钠?Six water piperazine and acetic anhydride were obtained by the reaction of anthelmintic piperazine NOx thiazole intermediates acetyl piperazine.
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