Drug Name: phentolamine mesylate tablet
English: Phentolamine Mesylate Dispersible Tablets
main components: the goods for the major components of phentolamine mesylate
traits: $ or like white tablets.
pharmacological effects: $ adrenal receptor alpha blocker, both α1 and α2 receptor, the vasodilator and reduce peripheral vascular resistance, will corpus cavernosum smooth muscle relaxation, blood more inflows in the corpus cavernosum, inhibition of blood outflow corpus cavernosum, resulting in erection. The drug can not maintain erectile function of sex hormones, emotions and nerves, to maintain and promote the long erection. The recommended dose of the drug to stimulate the lack of no effect.
Pharmacokinetics: 40mg of the oral goods, the best 30 minutes the time, sustained three to six hours, intravenous half-life of about 19 minutes. Major drug metabolism by the liver, approximately 13% of the drugs in urine from the prototype.
indications: used for the treatment of erectile dysfunction.
usage and consumption: oral, 40mg each in the first 30 minutes of taking life, taking a daily maximum, and the need for tolerance levels, adjustable to 60mg dose, the largest recommended dose of 80mg .
adverse reaction: common with nasal obstruction, palpitations, also leans flushing, dizziness, weakness, chest tightness and other adverse reactions, a few patients have heart rate, systolic blood pressure, diastolic blood pressure mild changes, with a few may of orthostatic hypotension.
of taboos: hypotension (<90mmHg systolic blood pressure, diastolic blood pressure <60mmHg), severe arteriosclerosis, angina, myocardial infarction, liver and kidney dysfunction, and the patients with gastric ulcer allergies are prohibited goods.
1. Elderly possibility of using this induced hypothermia increased.
2. Gong coronary vein insufficiency, a mental patient, anti-diabetic patients.
3. Drug interactions
(1) The materials combined with the effects of B Triprolidine, postural hypotension or bradycardia increasing incidence.
(2) Phenobarbital I. Mian energy sedative hypnotics, reserpine, buck-ling, antihypertensive agents to strengthen the role of antihypertensive drugs.
(3) combined with the cardiac glycosides, we can enhance its toxicity.
(4) should avoid iron combination.
(5) and nitroglycerin banned drugs combined.
specifications: (1) 40mg; (2) 60 mg.
Storage: shading confined preservation.
Validity: tentative two years.
Warning:The information is only as a reference for new drug researcher and the patients or doctors can't use it as prescription basis!
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