Molecular formula :
nature : alias micronamicin; Sagami adriamycin; 6-N'- dimethyl gentamicin; Sharjah adriamycin. From small spp.strain micromomospora sagamiensis and mutation of aminoglycoside antibiotics. Common sulfate, a white powder, odorless, tasteless. Soluble in water, soluble in organic solvents. Room temperature stable. Semi-hydrate for amorphous solids, melting point of 260 ° C (decomposition). Approximate spectrum antibiotic gentamicin, Gram-negative and positive bacteria are broad-spectrum bactericidal effect, and the amino-glycosides have acetyltransferase resistant effective. The mechanism of inhibition of bacterial protein synthesis, while the role of membrane damage. 0.5h after intramuscular plasma concentration reached its peak and is distributed widely and body fluids. Mainly by renal excretion. Can cause kidney toxicity, neuromuscular block, occasionally damage liver function and the changes in blood. Renal dysfunction and the elderly caution.
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