Original document(23 pages) Authorized document(23 pages) 中文版
    The present invention provides a novel thermosensitive cyclotriphosphazene-platinum complex conjugates represented by Formula (1) wherein m is a repeating unit of poly(alkoxyethylene glycol) selected from the integers 2, 7 and 12; n represents the length of the alkyl chain selected from the integers 0, 1, 2 and 3; x represents the length of the anionic amino acid residue selected from the integers 0 (amino malonic acid derivatives), 1 (aspartic acid derivatives) and 2 (glutamic acid derivatives); A2 is a bidentate chelating diamine selected from the group consisting of 2,2-dimethyl-1,3-propanediamine (dmpda), trans(+/-)-1,2-diaminocyclohexane (dach) and 1,1-diaminomethylcyclohexane (dmach).
Application Number
申请号
01802468 Application Date
申请日
2001.01.10
Title 名称 Thermosensitive cyclotriphosphazene-platinum complex conjugate, its preparation method and anticancer agent containing the same
Publication Number
公开号
1388808 Publication Date
公开日
2003.01.01
Approval Pub. Date 2005.04.06 Granted Pub. Date 2005.04.06
International Classification 分类号 C07F15/00;C07F9/00;A61K31/28
Applicant(s) Name
申请人
Koera Institute of Science and Technology
Address 地址
Inventor(s) Name 发明人 Sohn Younsoo;Song Soo-Chang;Lee Sangbeom
Attorney & Agent 代理人 huang gesheng lin bainan
More information 更  多  信  息


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