Original document(29 pages) Authorized document(27 pages) 中文版
    The present invention relates to novel N-substituted azaheterocyclic carboxcylic acids of the general formula wherein X, Y, Z, R1, R2 and r are as defined in the detailed part of the description, or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation as well as their use for treatment of indications caused by or related to the secretion and circulation of insulin antagonising peptides.
Application Number
申请号
01139357 Application Date
申请日
1997.10.02
Title 名称 N-substituted nitrogen heterocyclic compound
Publication Number
公开号
1403445 Publication Date
公开日
2003.03.19
Approval Pub. Date 2005.03.02 Granted Pub. Date 2005.03.02
International Classification 分类号 C07D207/08;C07D211/60;A61K31/40;A61K31/445;A61P3/10;A61P25/06;A61P25/00;A61P19/02;A61P17/00
Applicant(s) Name
申请人
Novo Nordisk A/S
Address 地址
Inventor(s) Name 发明人 H.S. Andesen;T.K. Tjaagensen;R. Horvig
Attorney & Agent 代理人 li ying
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