| Original document(23 pages) 中文版 |
HBsAg can be produced by cultivating yeast containing a recombinant DNA wherein a DNA in which a sequence complementary with the 3' end of 18S ribosomal RNA is added upstream of a DNA coding for hepatit is B virus surface antigen is bound just after a sequence complementary with the 3' end of 18S ribosomal RNA located at the 5' non-coding region of yeast repressible acid phosphatase gene. HBsAg thus obtained can be used as a vaccine to prevent HBV infection. |
Application Number
申请号 |
85107120 |
Application Date
申请日 |
1985.09.21 |
| Title 名称 |
Recombinant DNA and use thereof |
Publication Number
公开号 |
1009927 |
Publication Date
公开日 |
1987.04.01 |
| Approval Pub. Date |
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Granted Pub. Date |
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| International Classification 分类号 |
A61K39/29,C12N1/18,C12N15/00 |
Applicant(s) Name
申请人 |
Takeda Chemical Industries, Ltd. (JP) Osaka 541, Japan |
| Address 地址 |
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| Inventor(s) Name 发明人 |
Masakazu Kikuchi |
| Attorney & Agent 代理人 |
LUO HONG LIU YUANJIN |
| More information 更 多 信 息 |
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