| Original document(43 pages) Authorized document(41 pages) 中文版 |
Substituted benzamides of the general formula I I in which: R represents an alkoxy, alkenyloxy or alkynyloxy group containing up to 7 carbon atoms in the group, R1 is hydrogen or a NR4R5, or NR6COR7 group, where R4, R5 and R6, which may be the same or different, is each hydrogen or an alkyl group and R7 is an alkyl or trifluoromethyl group, R2 is hydrogen, halogen, or a nitro, or sulphamoyl group, R3 represents hydrogen or a methyl or methoxy group, X represents a hydrocarbon chain containing 1 to 4 carbon atoms, one of which may optionally be replaced by an oxygen atom, Y represents a non-aromatic cyclic ether or a non-aromatic cyclic thioether group and pharmaceutically acceptable salts thereof are useful in the treatment of gastro-intestinal disorders. Various methods of synthesis are described including synthesis via novel amines of the formula IIIa which are themselves obtained by reduction of the corresponding oximes. |
Application Number
申请号 |
86105972 |
Application Date
申请日 |
1986.08.06 |
| Title 名称 |
Preparation of benzamides |
Publication Number
公开号 |
1009901 |
Publication Date
公开日 |
1987.04.01 |
| Approval Pub. Date |
1993.11.24 |
Granted Pub. Date |
1993.11.24 |
| International Classification 分类号 |
A61K31/445;C07D211/58 |
Applicant(s) Name
申请人 |
Fordonal, S.A. |
| Address 地址 |
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| Inventor(s) Name 发明人 |
Armando Vega Noverola;Jose Manuel Prieto Soto |
| Attorney & Agent 代理人 |
LUO CAIXI |
| More information 更 多 信 息 |
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