| Original document(21 pages) 中文版 |
The invention relates to a process for the preparation of an azetidine-3-carboxylic acid of the formula I or a salt thereof, wherein R1 represents a hydrogen atom, a C1-6 alkyl or C3-8 cycloalkyl group or a group phenyl-CH(R3)- wherein R3 represents a hydrogen atom, a phenyl or an alkyl group of 1-4 carbon atoms, which process comprises reacting an azetidine of the formula II wherein R1 has the meanings defined above, and X represents a hydrogen atom, a carboxyl or a group, with an alkali metal base at a temperature of from 150 to 300 DEG C in the presence of a catalyst comprising a metal of the Group IIB of the Periodic System and/or a compound of said metal, and if desired converting the obtained azetidine-3-carboxylic acid salt into the corresponding acid; and to novel alkali, alkaline earth and quaternary ammonium salts of such acids. |
Application Number
申请号 |
86106702 |
Application Date
申请日 |
1986.09.29 |
| Title 名称 |
Process for the prepn. of an agetidine-3-carboxylic acid or salt thereof |
Publication Number
公开号 |
1009899 |
Publication Date
公开日 |
1987.04.01 |
| Approval Pub. Date |
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Granted Pub. Date |
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| International Classification 分类号 |
C07D205/04;C07F1/00;C07F3/00 |
Applicant(s) Name
申请人 |
Shell Internationale Research Maatschappij B.V. (NL) Carel Van Bylandtlaan 30, 2 |
| Address 地址 |
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| Inventor(s) Name 发明人 |
Gerhard DE Lind Van Wijngaarden;Jannetje DE Waal;Pieter Adriaan Verbrugge |
| Attorney & Agent 代理人 |
ZHANG YUANZHONG WANG JIE |
| More information 更 多 信 息 |
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