The present invention provides totle saponins compounds, especially use of totle saponins compounds obtained from plants. In particular, these totle saponins compounds can regulate central cholinergic N receptor, and do not combine with the excited combinative the point of N receptor, and do not affect cholinergic M disease of the central nervous system and schizophrenia, depression or the like relevant with central drug. The present invention provides a pharmaceutical composition for treating the disease relevant with central cholinergic N receptor. |