| Original document(9 pages) Authorized document(9 pages) 中文版 |
The present invention relates to an optical detecting apparatus for immunity reaction of magnetic separation type and detecting method thereof. The detecting apparatus consists chiefly of bottom plate optical wave-guide, immunity reaction pool and magnetic poles. The uses pack is used as a background matter by the magnetic particles with antibody. The content of antigen in a sample can be obtained through detecting the ratio of light intensities in the wave-guide before and after the immunity reaction of antigen-antibody or the variation of the critical angle of the whole reflection before and after the immunity reaction. In the method of the invention, because of the action of the magnetic poles, the magnetic particles in coordination with the resultant of the immunity reaction are absorbed to the bottom part of the immunity reaction pool so as to make the concentration of the solution (e.g. the concentration of the antigen) vary in the greatest. |
Application Number
申请号 |
02160691 |
Application Date
申请日 |
2002.12.30 |
| Title 名称 |
Magnetic separated immunoreaction optical inspecting device and method
|
Publication Number
公开号 |
1424584 |
Publication Date
公开日 |
2003.06.18 |
| Approval Pub. Date |
|
Granted Pub. Date |
2005.01.12 |
| International Classification 分类号 |
G01N21/55,G01N21/59,G01N33/537,G01N33/551 |
Applicant(s) Name
申请人 |
Shanghai Communication Univ. |
| Address 地址 |
200030 |
| Inventor(s) Name 发明人 |
Dou Xiaoming, Yu Changqing |
| Attorney & Agent 代理人 |
mao cuiying |
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