Synthetic process for intermediate for ecteinascidin and phthalascidin compounds

Original document(22 pages) Authorized document(20 pages) 中文版

An efficient process is described for the synthesis of 5, a key intermediate for the synthesis of the potent antitumor agents ecteinascidin (1) and phthalascidin (2) from the readily available building blocks 3b and 4.

Application Number 申请号	01807097	Application Date 申请日	2001.02.09
Title 名称	Synthetic process for intermediate for ecteinascidin and phthalascidin compounds
Publication Number 公开号	1425017	Publication Date 公开日	2003.06.18
Approval Pub. Date	2005.12.07	Granted Pub. Date	2005.12.07
International Classification 分类号	C07D498/18;C07D491/18
Applicant(s) Name 申请人	President and Fellows of Harvard College
Address 地址
Inventor(s) Name 发明人	E.J. Corey
Attorney & Agent 代理人	huang yifen wu xiaonan

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