Original document(40 pages)  中文版
    The present invention provides recombinant yellow fever viruses, particularly live attenuated recombinant, which comprise exogenous nucleotide sequences which encode exogenous amino acid sequences. These recombinant yellow fever viruses comprise an exogenous nucleic acid. Infection of a host cell with a recombinant yellow fever provides for expression of the exogenous nucleic acid in a host cell and production of an antigenic polypeptide encoded by the exogenous nucleic acid. Such recombinant yellow fever are useful in eliciting an immune response to the exogenous polypeptide.
Application Number
申请号
01803881 Application Date
申请日
2001.01.19
Title 名称 Recombinant flaviviruses and methods of use thereof
Publication Number
公开号
1398297 Publication Date
公开日
2003.02.19
Approval Pub. Date Granted Pub. Date
International Classification 分类号 A61K39/00;A61K48/00;C12N5/10;C12N7/01;C12N15/62;C12N15/86
Applicant(s) Name
申请人
Regents of Univ of California
Address 地址
Inventor(s) Name 发明人 R Andino-Pavlovsky;A. Mcallister-Moreno
Attorney & Agent 代理人 xu xun
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