| Original document(39 pages) 中文版 |
The present invention relates to a process of fragmenting and labeling a synthetic or natural nucleic acid, comprising the steps of: providing a mixture containing a nucleic acid, a labeling agent containing a detectable label, and at least one multivalent metal cation in a substantially aqueous solution; chemically fragmenting the nucleic acid in the mixture to produce a multiplicity of nucleic acid fragments; and attaching at least one label to at least one of the nucleic acid fragments to produce a detectably labeled nucleic acid fragment. |
Application Number
申请号 |
99817075 |
Application Date
申请日 |
1999.12.17 |
| Title 名称 |
Process for labeling nucleic acid |
Publication Number
公开号 |
1398301 |
Publication Date
公开日 |
2003.02.19 |
| Approval Pub. Date |
|
Granted Pub. Date |
|
| International Classification 分类号 |
C12Q1/68 |
Applicant(s) Name
申请人 |
Bio Merieux |
| Address 地址 |
|
| Inventor(s) Name 发明人 |
A.R. Banerjee, M.M. Becker |
| Attorney & Agent 代理人 |
li huayang |
| More information 更 多 信 息 |
|
| Related patents information |
|
|
|
|
|
|