The invention provides a device for continuing delivering an antiacne pharmaceutical preparation to a specific site for a long period. The patch has a lining membrane layer, a release liner and one or more matrix layers which are used as a carrier for the antiacne pharmaceutical preparation or together with the carrier, characterized in that the patch type device includes at least two kinds of anti-acne formulation comprising an effective amount of at least two kinds of active ingredients selected from the group of at least two kinds of different active ingredients and the group of at least the two kinds of the different active ingredients is composed by selection from the group consisting of a keratolytic agent, an antiirritation agent, a bactericide, an antimicrobial agent, a hormonal agent, a hormonal agonist, a hormone antagonist and other agents suitable for treatment of the acne. |