| Original document(9 pages) 中文版 |
The present invention provides one kind of slow-releasing basic fibroblast growdth factor (bFGF) microsphere and its preparation and use. The microsphere has coated bFGF as medicine, and matrix of polylactide-co-glycolide (PLGa). The slow-releasing bFGF microsphere is prepared by using PVA or mixed PVA-PEG liquid as dispersing medium and through w/o/wt% re-emulsion and drying process and mechanical stirring. Its freeze dried power has good dispersivity and low organic solvent residue. The present invention can be used for local administration or vein administration of treating fracture, bone defect and other diseases. |
Application Number 申请号 |
02133476 |
Application Date 申请日 |
2002.07.15 |
| Title 名称 |
Slow-releasing bFGF-PLGA microball and its prepn and use |
Publication Number 公开号 |
1398584 |
Publication Date 公开日 |
2003.02.26 |
| Approval Pub. Date |
|
Granted Pub. Date |
|
| International Classification 分类号 |
A61K9/16,A61K9/52,A61K38/18,A61P19/08 |
Applicant(s) Name 申请人 |
Pei Fuxing |
| Address 地址 |
610041 |
| Inventor(s) Name 发明人 |
Pei Fuxing, Duan Hong |
| Attorney & Agent 代理人 |
|
| More information 更 多 信 息 |
|
|
|