| Original document(9 pages) 中文版 |
In the present invention the microsphere has coated bFGF as medicine, and matrix of lactic acid-glycol copolymer (PLA-PEG). The slow-releasing bFGF microsphere is prepared by using PVA-PEG mixed liquid as dispersing medium and through evaporation and mechanical stirring. It has excellent slow-releasing performance of over two-week releasing period. Its freeze dried powder has good dispersivity and low organic solvent residue. The present invention can be used for local administration or vein administration of treating fracture, bone defect and other diseases. |
Application Number
申请号 |
02133477 |
Application Date
申请日 |
2002.07.15 |
| Title 名称 |
Slow-releasing bFGF-PLA-PEG microball and its prepn and use |
Publication Number
公开号 |
1398585 |
Publication Date
公开日 |
2003.02.26 |
| Approval Pub. Date |
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Granted Pub. Date |
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| International Classification 分类号 |
A61K9/16,A61K9/52,A61K38/18,A61P17/08 |
Applicant(s) Name
申请人 |
Pei Fuxing |
| Address 地址 |
610041 |
| Inventor(s) Name 发明人 |
Pei Fuxing, Duan Hong |
| Attorney & Agent 代理人 |
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| More information 更 多 信 息 |
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