| Original document(37 pages) Authorized document(37 pages) 中文版 |
The present invention discloses a kind of human vessel IBP-like growth factor polypeptide (VIGF), DNA (RNA) encoding this polypeptide and a recombinant technological process of producing this polypeptide. The present invention also discloses the method of applying the polypeptide to healing wound, tissue regeneration and promoting implant fixation and vascularization. The present invention also discloses an antagonist against this polypeptide and its application as treating agent for treating athersclerosis, tumor and cicatrisation. In addition, the present invention also discloses the diagnosis method of identifying mutation in VIGF nucleic acid sequence and VIGF polypeptide altering level. Especially, the present invention relates to the application of VIGF antibody to diagnosing blood vessel diseases and tumogenesis related new vascularization. |
Application Number
申请号 |
02119142 |
Application Date
申请日 |
1994.12.09 |
| Title 名称 |
Human vascular IBP-like growth factor |
Publication Number
公开号 |
1399133 |
Publication Date
公开日 |
2003.02.26 |
| Approval Pub. Date |
|
Granted Pub. Date |
2004.09.15 |
| International Classification 分类号 |
C07K14/475,C12N15/00 |
Applicant(s) Name
申请人 |
Human Genome Sciences, Inc. |
| Address 地址 |
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| Inventor(s) Name 发明人 |
G.A. Hastings |
| Attorney & Agent 代理人 |
lin xiaogong |
| More information 更 多 信 息 |
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