Original document(76 pages)  中文版
    The invention provides methods identifying individuals suitable for treatment for lupus and methods of monitoring treatment, based on measuring antibody affinities, as well as of treating lupus based on measuring antibody affinities. The treatment entails administration of a conjugate comprising a non-immunogenic valency platform molecule and at least two double stranded DNA epitopes, such as DNA molecules, which bind to anti-DNA antibodies from the patient.
Application Number
申请号		 00816224 Application Date
申请日		 2000.11.28
Title 名称 Method of treating lupus based on antibody affinity and screening methods and compositions for use thereof
Publication Number
公开号		 1399562 Publication Date
公开日		 2003.02.26
Approval Pub. Date Granted Pub. Date
International Classification 分类号 A61K47/48;G01N33/564
Applicant(s) Name
申请人		 La Jolla Pharmaceutical Co.
Address 地址
Inventor(s) Name 发明人 M.D. Linnik;P.A. Mcneeley
Attorney & Agent 代理人 tang weijie
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