| Original document(61 pages) Authorized document(63 pages) 中文版 |
The invention is based on the discovery that compounds of Formula (I), are unexpectedly highly potent and selective inhibitors of the adenosine A1 receptor. Adenosine A1 antagonists can be useful in the prevention and/or treatment of numerous diseases, including cardiac and circulatory disorders, degenerative disorders of the central nervous system, respiratory disorders, and many diseases for which diuretic treatment is suitable. In one embodiment, the invention features a compound of formula (I). |
Application Number
申请号 |
00816198 |
Application Date
申请日 |
2000.11.13 |
| Title 名称 |
Adenosine receptor antagonists and methods of making and using the same |
Publication Number
公开号 |
1399636 |
Publication Date
公开日 |
2003.02.26 |
| Approval Pub. Date |
2005.02.02 |
Granted Pub. Date |
2005.02.02 |
| International Classification 分类号 |
A61K31/505;A61K31/52;A61P9/00;C07D473/06 |
Applicant(s) Name
申请人 |
Biogen, Inc. |
| Address 地址 |
|
| Inventor(s) Name 发明人 |
J.E. Dowling;C. Ensinger;G. Kumaravel et.al |
| Attorney & Agent 代理人 |
du jingyang |
| More information 更 多 信 息 |
|
| Related patents information |
|
|
|
|
|
|