The present invention relates to a packaging and applicator device comprising a compartment for receiving a receptacle containing a substance; a applicator capable of being releasably fixed to the device; a first opening through which the applicator can take the substance; a shutter associated with the first opening and capable of taking a closed position and an opened position; a transmission member capable of being driven in displacement by the applicator to move the shutter into at least one of the open and closed positions; and a second opening distinct from the first and through which the receptacle can be inserted in said compartment, by being moved relative to the transmission member. |