Original document(31 pages)  中文版
    In the whole-sequence (PreS1+PreS2+S) is natural hepatitis B virus surface antigen, the DNA code which is not suitable for translating amino acids in yeast cell is modified to create the DNA sequence PreS1+PreS2+S which features that more amino acids at terminal N' of said natural sequence are cut out. The new sequence is used to configure the expression strain of genetically engineered yeast for expressing new hepatitis B surface antigen, which can be used as vaccine to generate specific Hbs, PreS1 and PreS2 antibodies.
Application Number
申请号		 02159941 Application Date
申请日		 2002.12.30
Title 名称 Gene modification sequence of gene recombination hepatitis virus surface antigen and its product
Publication Number
公开号		 1429908 Publication Date
公开日		 2003.07.16
Approval Pub. Date Granted Pub. Date
International Classification 分类号 A61K39/29,A61K39/42,A61P1/16,C12N1/19,C12N15/51,C12N15/81,C12P21/02,C12Q1/70
Applicant(s) Name
申请人		 Wuhan Baiao Bioengineering Co., Ltd.
Address 地址 430060
Inventor(s) Name 发明人 Bai Xianhe
Attorney & Agent 代理人
More information 更  多  信  息


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