| Original document(14 pages) Authorized document(14 pages) 中文版 |
A process for preparing heparin oligose from heparinase includes such steps as culturing sphingobacterium (CGMCC No.0660), preparing non-cell coarse enzyme liquid, extracting and purifying heparinase, degradating heparin by the heparinase at 20-30 deg.C to obtain heparin oligose mixture, ultrafilter, gel filter for fractionation and evaporation concentration. The product has the activity of resisting smooth muscle hyperplasia. |
Application Number 申请号 |
02148066 |
Application Date 申请日 |
2002.10.24 |
| Title 名称 |
Method of producing heparin oligosaccharide using heparinase |
Publication Number 公开号 |
1429913 |
Publication Date 公开日 |
2003.07.16 |
| Approval Pub. Date |
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Granted Pub. Date |
2006.03.08 |
| International Classification 分类号 |
C12P19/00,C12R1/01 |
Applicant(s) Name 申请人 |
Microbiological Inst., Chinese Academy of Sciences |
| Address 地址 |
100080 |
| Inventor(s) Name 发明人 |
Cheng Xiulan, Yang Jing |
| Attorney & Agent 代理人 |
jiang zhaoyuan |
| More information 更 多 信 息 |
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