A process for configuring multi-type, high-titer, high-abundance and high-diversity antibody libraries and antigen libraries in procaryotic cell and eukaryotic cell is disclosed, which features use of procaryotic and eukaryotic cell reproduction expression. Its screening features that according to the DNA sequence of antigen epitope gene, the all or part of the open reading frames for antigen gene and the special protein coding gene are combined to form fusion gene for screening the high-specificity and-affinity antibody. |