| Original document(32 pages) 中文版 |
The invention is confluens protein of SARS virus S protein and N protein, and the manufacturing, application and the gene project technology, vaccine and diagnosing reductant. Through analyzing the cistine series of SARS s protein and N protein, sifts out SARS virus S protein segment with strong antigen epitope, namely the 162nd cistine to 460nd cistine, and the N protein segment of SARS virus with strong antigen epitope, anmely the first cistine to 258nd cistine. It synthesizes the new SARS virus S protein segment and N protein segment gene series, connects the two gene segments in series. Expresses the confluens protein of the two protein segments, the two are connected by glycine and serine, inserts a glycine adjoining to the frist cistine methionine of N protein segment, the confluens protein length is 560 cistines. |
Application Number
申请号 |
03132162 |
Application Date
申请日 |
2003.07.03 |
| Title 名称 |
SARS virus S protein and N protein fusion protein, and preparation and use thereof
|
Publication Number
公开号 |
1488646 |
Publication Date
公开日 |
2004.04.14 |
| Approval Pub. Date |
|
Granted Pub. Date |
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| International Classification 分类号 |
A61K39/215,A61P11/00,A61P31/14,C07K16/08,C07K19/00,C12N15/62,C12N15/63,G01N33/68 |
Applicant(s) Name
申请人 |
Li Yuexi |
| Address 地址 |
210002 |
| Inventor(s) Name 发明人 |
Li Yuexi, Tao Kaihua |
| Attorney & Agent 代理人 |
xi shengyuan |
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