| Original document(12 pages) 中文版 |
The present invention belongs to the field of pharmaceutical technology and relates to transdermal Ligustrazine plaster and its preparation. It has Ligustrazine phosphate or Ligustrazine as active medicinal component and consists of medicine storing back, adhering layer, release controlling film, back lining layer and protective layer. It is superior to available Ligustrazine preparation forms in medicine releasing are, transdermal rate and lasting release time, and has the features of determined curative effect, stable quality, high safety, etc. Animal experiments show that the plaster can retard the effect of ischemic to cerebral damage, inhibit thrombosis caused by tissue damage, prevent and treat cerebral embolism and maintain balanced medicine density in blood for 24 hr; and has light irritation to skin, no irritability and no toxic reaction. |
Application Number
申请号 |
02157693 |
Application Date
申请日 |
2002.12.24 |
| Title 名称 |
Transdermal Ligustrazine plaster and its prepn |
Publication Number
公开号 |
1432363 |
Publication Date
公开日 |
2003.07.30 |
| Approval Pub. Date |
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Granted Pub. Date |
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| International Classification 分类号 |
A61K9/70,A61K31/4965,A61M37/00,A61P9/10 |
Applicant(s) Name
申请人 |
Fudan Univ. |
| Address 地址 |
200433 |
| Inventor(s) Name 发明人 |
Shen Teng, Xu Huinan |
| Attorney & Agent 代理人 |
bao zhaoyi |
| More information 更 多 信 息 |
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