Original document(64 pages)  中文版
    A nucleic acid delivery complex is provided which comprises a condensed polypeptide/nucleic acid complex and a cationic lipid wherein the complex comprises (a) a nucleic acide sequence of interest (NOI); and (b) one or more viral nucleic acid packaging polypeptides, or derivatives thereof, said polypeptides or derivatives thereof being (i) capable of binding to the NOI; and (ii) capable of condensing the NOI; and wherein the NOI is heterologous to the polypeptide. Also provided is a method of introducing an NOI into a cell using the delivery vector.
Application Number
申请号
00819146 Application Date
申请日
2000.12.12
Title 名称 Viral core protein-cationic lipid-nucleic acid-delivery complexes
Publication Number
公开号
1434870 Publication Date
公开日
2003.08.06
Approval Pub. Date Granted Pub. Date
International Classification 分类号 A61K47/48;C07K14/075;C12N15/34;C12N15/88
Applicant(s) Name
申请人
Mitsubishi Pharmaceuticals Inc.
Address 地址
Inventor(s) Name 发明人 T. Tagawa;A.D. Miller;E. Perouzel
Attorney & Agent 代理人 zhang anyu meng fanhong
More information 更  多  信  息


 Related patents information
Google
Note:All patent data come from State Intellectual Property Office of the People's Republic of China. If there were discrepancies between here and the State Intellectual Property office, the later is more accurate. The patent data is only for public exchange and learning purposes. We are not responsible for the adverse consequences with unverified use of the data.