| Original document(34 pages) 中文版 |
The present invention relates to a method of qualitatively and/or quantitatively monitoring the progress of a lymphoid neoplasia in a mammal and, more particularly, to a method of monitoring the progress of a lymphoid neoplasia utilising a molecular screening technique. The method of the present invention is useful in a range of applications including, but not limited to, monitoring the progression of a neoplastic lymphoid disease condition, monitoring the levels of neoplastic lymphoid cells during remission, predicting the likelihood of a subject's relapse from a remissive state to disease state or for assessing the effectiveness of existing therapeutic drugs and/or new therapeutic agents. In a related aspect, the present invention also provides a method for qualitatively and/or quantitatively detecting clonal lymphocyte populations in a mammal and, more particularly, for detecting multiple clonal lymphocyte populations in a subject such as where a neoplastic lymphoid cell has undergone somatic gene rearrangement thereby forming a new and genetically distinct clonal population or such as where one or several clonal lymphocyte populations contribute to an immunological response. |
Application Number
申请号 |
01810299 |
Application Date
申请日 |
2001.04.12 |
| Title 名称 |
Method of detecting neoplastic or non-neoplastic cells |
Publication Number
公开号 |
1434875 |
Publication Date
公开日 |
2003.08.06 |
| Approval Pub. Date |
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Granted Pub. Date |
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| International Classification 分类号 |
C12Q1/68 |
Applicant(s) Name
申请人 |
Monokunt Co., Ltd. |
| Address 地址 |
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| Inventor(s) Name 发明人 |
A.A. Morley;P.J. Sykes;M.J. Brisco |
| Attorney & Agent 代理人 |
cheng yong |
| More information 更 多 信 息 |
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