| Original document(21 pages) 中文版 |
The invention discloses an isoquinoline derivant. The said derivant, with 9,10-dimethoxy -[1,3] dioxide [4,5-g] isoquinoline [3,2-a] isoquinoline -7-ylidehydrochlorate (I) as its representative, reduces plasma cholesterol level by massively absorbing low density lipoprotein cholesterol and changing them to bile acid in liver. The 9,10-dimethoxy -[1,3] dioxide [4,5-g] isoquinoline [3,2-a] isoquinoline-7-ylidehydrochlorate is a new cholesterol lowering compound which is different in cholesterol lowering mechanism from statins. The 9,10-dimethoxy -[1,3] dioxide [4,5-g] isoquinoline [3,2-a] isoquinoline -7-ylidehydrochlorate and other isoquinoline derivants have an extremely low side toxiceffect, so they are safe natural cholesterol lowering compounds. |
Application Number
申请号 |
200510024211 |
Application Date
申请日 |
2005.03.04 |
| Title 名称 |
Isoquinoline derivatives and their preparation process and application |
Publication Number
公开号 |
1827618 |
Publication Date
公开日 |
2006.09.06 |
| Approval Pub. Date |
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Granted Pub. Date |
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| International Classification 分类号 |
C07D455/00,A61K31/4745,A61P9/10,A61P3/06,A23K1/16 |
Applicant(s) Name
申请人 |
Zhou Guihua |
| Address 地址 |
200000 |
| Inventor(s) Name 发明人 |
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| Attorney & Agent 代理人 |
fei kaikui ji liangjiu |
| More information 更 多 信 息 |
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