| Original document(73 pages) 中文版 |
Described are novel compounds with neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity of the general formula (I), wherein the substituents R<1>, R<2> , R<3> and R<4> have the meanings given in the description and also medicaments containing these compounds, in particular medicaments suitable for treating or preventing cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis. |
Application Number 申请号 |
200480027747 |
Application Date 申请日 |
2004.09.23 |
| Title 名称 |
Amidomethyl substituted 1-(carboxyalkyl)-cyclopentylcarbonylamino-benzazepine-N-acetic acid derivatives, process and intermediate products for their preparation and medicaments containing these compou |
Publication Number 公开号 |
1856501 |
Publication Date 公开日 |
2006.11.01 |
| Approval Pub. Date |
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Granted Pub. Date |
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| International Classification 分类号 |
C07K5/06,A61K38/05,A61P9/12 |
Applicant(s) Name 申请人 |
Solvay Pharm GmbH |
| Address 地址 |
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| Inventor(s) Name 发明人 |
Hoeltje Dagmar, Fischer Yvan, Ziegler Dieter, Weske Michael, Michaelis Kathrin, Karimi-Nejad Yasmin, Messinger Josef, Pahl Axel, Hoefer Constanze, Ikonomidou Hrissanthi |
| Attorney & Agent 代理人 |
wu yihua |
| More information 更 多 信 息 |
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