A process for preparing the animal model of the cerebral cortex damage caused by local ischemia and refilling includes such steps as anesthetizing an animal, exposing the target cerebral cortex region, putting a thread segment made of fine thread (50-1000 microns in diameter) or a closed ring on said target region, binding the meninges, artery branch and said fine thread together, observing the position and volume of cerebral infarction or evaluating the function damage degree, and refilling by removing said fine thread. |