The invention relates to a method used to process directional inducing differentiation for the adipose tissue stem cell from vitro to adipose and endothelial cell, combine the processed the cell with biomaterial to form engineering adipose tissue which belongs to biomedicine field. It produced adipose tissue can be used to remedy soft tissue defect, repair wound tissue, and fill in normal tissue, such as face and neck tumor cutting, various complex wound, congenital malformation repair, etc. Thus it has huge market value potential and wide application prospect. |