Quinoline intermediates of receptor tyrosine kinase inhibitors and the synthesis thereof

Original document(55 pages) 中文版

This invention is directed to methods of preparing 4-substituted quinoline compounds as intermediates in the manufacture of receptor tyrosine kinase inhibitors and intermediate compounds used in the methods thereof, wherein the 4-substituted quinoline compound has the general formula (I); and wherein substitutions at LG'', PG, A, G, R1 and R4 are set forth in the specification.

Application Number
申请号

200580007748

Application Date
申请日

2005.01.14

Title 名称

Quinoline intermediates of receptor tyrosine kinase inhibitors and the synthesis thereof

Publication Number
公开号

1930128

Publication Date
公开日

2007.03.14

Approval Pub. Date

Granted Pub. Date

International Classification 分类号

C07D215/54;C07D295/14;C07D413/04

Applicant(s) Name
申请人

Wyeth Corp.

Address 地址

Inventor(s) Name 发明人

Attorney & Agent 代理人

lilian tao

More information 更多信息

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