Original document(145 pages)  中文版
    Compounds and methods for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonists, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt, solvate or prodrug thereof, wherein D, X, Y, R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7> and R<8> are as defined herein.
Application Number
申请号
200580007098 Application Date
申请日
2005.02.25
Title 名称 Diaminopyrimidines as P2X3 and P2X2/3 antagonists
Publication Number
公开号
1930135 Publication Date
公开日
2007.03.14
Approval Pub. Date Granted Pub. Date
International Classification 分类号 C07D239/48;C07D409/12;C07D403/12;C07D405/12;C07D413/12;C07D417/12;A61K31/505;A61P13/00
Applicant(s) Name
申请人
Hoffmann La Roche
Address 地址
Inventor(s) Name 发明人
Attorney & Agent 代理人 huangge sheng linbai nan
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