The oil-in-water type nanometer emulsion oral liquid of peonol consists of surfactant, oil, peonol and distilled water. Its preparation process includes the following steps:weighing surfactant with or without co-surfactant; calculating HLB value and selecting oil for reaching emulsifying HLB value near that of the surfactant phase; changing the ratio between the surfactant phase and the oil phase regularly to dissolve peonol in the surfactant; adding distilled water slowly at 20-25 deg.c to form clear and flowing O/W type stable nanometer emulsion oral liquid. The nanometer emulsion oral liquid has high dissolubility of peonol, raised bioavailability of peonol, delayed the time for the medicine to be metabolized in the body, reduced supplementary material amount, low production cost and wide medicine market foreground. |