The present invention is one kind of slow released capsule with slow released indapamide microcapsule as main component and homogeneous medicine release. The slow released microcapsule includes medicine microcapsule with indapamide as active component and slow releasing coating layer around the medicine microcapsule. The supplementary material includes supplementary material to constitute the medicine microcapsule together with indapamide and the slow releasing material. In the slow released microcapsule, the weight ratio of indapamide, the supplementary material and the slow releasing material is 0.5-3.0 to 1-10 to 165-400. The slow released microcapsule is prepared through a coating process. The slow released preparation of the present invention has prolonged in vivo residence time of the medicine, controlled medicine release, lowered toxic side effect and raised curative effect. |