| Original document(88 pages) 中文版 |
A fused heterocycle derivative represented by the following general formula (I), a pharmacologically acceptable salt thereof, or a prodrug of either [in the formula, R<1> to R<4> each is hydrogen, OH, amino, etc.;R<5> and R<6> each is hydrogen, OH, halogeno, optionally substituted alkyl, etc.; Q is alkylene, alkenylene, etc.; ring A is aryl or heteroaryl; the ring (R1) shown below is any of the rings (R2) shown below; and G is a group represented by the following general formula (G-1) or (G-2) (wherein E<1> is hydrogen, fluorine, or OH; and E<2> is hydrogen, fluorine, methyl, etc.)]. They have human SGLT inhibitory activity and are useful as a preventive or therapeutic agent for diseases attributable to hyperglycemia, such as diabetes, postprandial hyperglycemia, impaired glucose tolerance, complications of diabetes, and obesity. |
Application Number
申请号 |
200580006965 |
Application Date
申请日 |
2005.03.03 |
| Title 名称 |
Fused heterocycle derivative, medicinal composition containing the same, and medicinal use thereof |
Publication Number
公开号 |
1934103 |
Publication Date
公开日 |
2007.03.21 |
| Approval Pub. Date |
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Granted Pub. Date |
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| International Classification 分类号 |
C07D405/04;A61K31/351;A61K31/381;A61K31/404;A61K45/00;A61P3/04;A61P3/06;A61P3/10;A61P7/10;A61P9/04;A61P9/10;A61P9/12;A61P19/06;A61P43/00;C07D407/04;C07D409/04 |
Applicant(s) Name
申请人 |
Kissei Pharmaceutical |
| Address 地址 |
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| Inventor(s) Name 发明人 |
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| Attorney & Agent 代理人 |
wanghai chuan fanwei min |
| More information 更 多 信 息 |
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