Original document(27 pages)  中文版
    A solid pharmaceutical preparation of solifenacin or a salt thereof, the preparation being stable and inhibited from decomposing with time when supplied to clinical fields. In a pharmaceutical preparation containing solifenacin or a salt thereof, the compound in an amorphous form was revealed to be causative of cardinal-drug decomposition with time. The composition for a solid pharmaceutical preparation of solifenacin or a salt thereof contains solifenacin or its salt each in a crystalline form, and the content of the compound in an amorphous form in the composition is within the range which exerts no influence on product stability. Also provided are: a process for producing the composition; and a medicinal composition for solid pharmaceutical preparations which contains solifenacin and an amorphization inhibitor.
Application Number
申请号
200580009495 Application Date
申请日
2005.03.24
Title 名称 Composition for solid pharmaceutical preparation of solifenacin or salt thereof
Publication Number
公开号
1934109 Publication Date
公开日
2007.03.21
Approval Pub. Date Granted Pub. Date
International Classification 分类号 C07D453/02;A61K9/20;A61K31/439;A61K47/34;A61P1/12;A61P13/02;A61P27/08
Applicant(s) Name
申请人
Astellas Pharma Inc.
Address 地址
Inventor(s) Name 发明人
Attorney & Agent 代理人 dingye beng zhangtian shu
More information 更  多  信  息


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