Original document(442 pages)  中文版
    This invention relates to benzopyran derivatives of formula (I) or (II), or pharmaceutically acceptable salts thereof wherein R<1> and R<2> are independently of each other hydrogen atom, C1-6alkyl group or C6-14aryl group, R<3> is hydrogen atom or C1-6alkylcarbonyloxy group, or together with R<4> forms a bond, R<4> is hydrogen atom, or together with R<3> forms a bond, m is an integer of 0 to 4, n is an integer of 0 to 4, V is a single bond, CR<7>R<8>, NR<9>, O, S, SO or SO2, R<5> is hydrogen atom or C1-6alkyl group, R<6> is hydrogen atom, C1-6alkyl group, C3-8cycloalkyl group, C3-8cycloalkenyl group, amino group, C1-6alkylamino group, di-C1-6alkylamino group, C6-14arylamino group, C2-9heteroarylamino group, C6-14aryl group, C2-9heteroaryl group or C2-9heterocyclyl group, A is 5-, 6- or 7-member ring fused with benzene ring, as constituent atom of the ring, oxygen atom, nitrogen atom or sulfur atom may be contained in the number of 1 to 3 alone or in a combination thereof, the number of unsaturated bond in the ring is 1, 2 or 3 including an unsaturated bond of the benzene ring to be fused, carbon atoms constituting the ring may be carbonyl or thiocarbonyl. These compounds are useful as an anti-arrhythmic agent.
Application Number
申请号
200580009029 Application Date
申请日
2005.03.23
Title 名称 Tricyclic benzopyran compound as anti-arrhythmic agents
Publication Number
公开号
1934116 Publication Date
公开日
2007.03.21
Approval Pub. Date Granted Pub. Date
International Classification 分类号 C07D491/04;C07D498/04;C07D513/04;C07D515/04;A61K31/436;A61P9/06
Applicant(s) Name
申请人
Nissan Chemical Ind Ltd.
Address 地址
Inventor(s) Name 发明人
Attorney & Agent 代理人 huangge sheng anpei dong
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