Original document(81 pages)  中文版
    A nitrogenous fused-ring derivative represented by the following general formula (I), a pharmacologically acceptable salt thereof, or a prodrug of either. They have human SGLT inhibitory activity and are useful as a preventive or therapeutic agent for diseases attributable to hyperglycemia, such as diabetes, postprandial hyperglycemia, impaired glucose tolerance, complications of diabetes, and obesity. [In the formula (I), one of R<1> and R<4> represents a group represented by the following general formula (S) (wherein R<5> and R<6> each represents H, OH, halogeno, etc.; Q represents alkylene, etc.; and ring A represents aryl, etc.) and the other represents H, OH, amino, etc.; R<2> and R<3> each represents H, OH, amino, halogeno, optionally substituted alkyl, etc.; A<1> represents O, S, etc.; A<2> represents CH or N; and G represents a group represented by the following general formula (G-1) (wherein E<1> is H, F, or OH and E<2> represents H, F, methyl, etc.) or the group represented by the following general formula (G-2).
Application Number
申请号
200580006211 Application Date
申请日
2005.03.03
Title 名称 Fused heterocycle derivative, medicinal composition containing the same, and medicinal use thereof
Publication Number
公开号
1934122 Publication Date
公开日
2007.03.21
Approval Pub. Date Granted Pub. Date
International Classification 分类号 C07H17/00;A61K31/7042;A61P3/04;A61P3/06;A61P3/10;A61P7/10;A61P9/10;A61P9/12;A61P19/06
Applicant(s) Name
申请人
Kissei Pharmaceutical
Address 地址
Inventor(s) Name 发明人
Attorney & Agent 代理人 liuhui yangjing
More information 更  多  信  息


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