| Original document(33 pages) 中文版 |
Processes are described for epoxidation reactions. In particular, the process comprises the conversion of a steroid substrate having an olefinic unsaturation in the steroid nucleus to a structure comprising a 9,11-epoxy substituent by reaction of the substrate with a peroxide compound in the presence of a peroxide activator. The epoxidation processes described are conducted at relatively low hydrogen peroxide to steroid substrate ratio. Several optional process modifications are described. |
Application Number
申请号 |
200580009358 |
Application Date
申请日 |
2005.03.22 |
| Title 名称 |
Process for the preparation of 9, 11 epoxy steroids |
Publication Number
公开号 |
1934126 |
Publication Date
公开日 |
2007.03.21 |
| Approval Pub. Date |
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Granted Pub. Date |
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| International Classification 分类号 |
C07J71/00 |
Applicant(s) Name
申请人 |
Pharmacia & Upjohn Company LLC |
| Address 地址 |
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| Inventor(s) Name 发明人 |
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| Attorney & Agent 代理人 |
shacha |
| More information 更 多 信 息 |
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