Original document(46 pages)  中文版
    The invention provides methods for preparing polymers bearing a terminal propionic acid. The method involves first reacting a water soluble and non-peptidic polymer comprising at least one hydroxyl group with a tertiary alkyl acrylate in the presence of a catalyst to form a propionic acid ester of the polymer, wherein the polymer has a weight average molecular weight of at least about 10,000 Da; and then treating the propionic acid ester of the polymer with a strong acid to form a propionic acid of the polymer.
Application Number
申请号		 200580008994 Application Date
申请日		 2005.01.21
Title 名称 Method of preparing propionic acid-terminated polymers
Publication Number
公开号		 1934143 Publication Date
公开日		 2007.03.21
Approval Pub. Date Granted Pub. Date
International Classification 分类号 C08F8/14;C08F8/12;C08G65/332;C07C67/31
Applicant(s) Name
申请人		 Nektar Therapeutics Al Corp.
Address 地址
Inventor(s) Name 发明人
Attorney & Agent 代理人 liuhui yangjing
More information 更  多  信  息


 Related patents information
Method of preparing carboxylic acid functionalized polymers
Google
Note:All patent data come from State Intellectual Property Office of the People's Republic of China. If there were discrepancies between here and the State Intellectual Property office, the later is more accurate. The patent data is only for public exchange and learning purposes. We are not responsible for the adverse consequences with unverified use of the data.