Original document(77 pages)  中文版
    The present invention relates to novel methods for the detection of substances capable of modulating or inhibiting pathological tau-tau protein association and pathological neurofilament aggregation. The methods of the present invention are particularly useful in screening substances for the prophylaxis and treatment of Alzheimer's disease, motor neuron disease, Lewy body disease, Pick's disease and progressive supranuclear palsy. In addition, substances capable of selectively inhibiting pathological aggregates while preserving normal cytoskeletal function are described.
Application Number
申请号		 200610100661 Application Date
申请日		 1996.03.25
Title 名称 Inhibition of Tau-Tau-association
Publication Number
公开号		 1935143 Publication Date
公开日		 2007.03.28
Approval Pub. Date Granted Pub. Date
International Classification 分类号 A61K31/5415;A61P25/00;A61P25/28
Applicant(s) Name
申请人		 Univ Aberdeen
Address 地址
Inventor(s) Name 发明人
Attorney & Agent 代理人 wuxiao nan bianxin qin
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