Original document(51 pages)  中文版
    Disclosed are methods and systems that use fluorescence polarization to identify compounds that have the ability to bind to, and/or modulate, the activity of the Receptor for Advanced Glycated Endproducts (RAGE). Compounds identified using the methods and systems of the present invention may comprise small organic molecule RAGE antagonists. The small organic molecule RAGE antagonists identified using the methods and systems of the present invention may be used to treat RAGE-mediated diseases, such as, but not limited to, diabetes or Alzheimer's disease.
Application Number
申请号
200580008732 Application Date
申请日
2005.03.18
Title 名称 Fluorescence polarization assay
Publication Number
公开号
1938591 Publication Date
公开日
2007.03.28
Approval Pub. Date Granted Pub. Date
International Classification 分类号 G01N33/53;G01N33/566
Applicant(s) Name
申请人
Transtech Pharma Inc.
Address 地址
Inventor(s) Name 发明人
Attorney & Agent 代理人 yangjing fanwei min
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